wick shredder vindicta

Always a good idea to have at least one form of regen in lane - Mystic Regeneration is a great option on Vindicta and easy to proc with the crow
Major powerspike at 3.4k souls when the snipe is unlocked
Focus on securing snipe kills early game.

Healing rite is a great option in a tough lane with a lot of poke damage
Guardian ward is a great defensive item against pick characters or characters that like to dive you
Extra health will eventually be upgraded into Fortitude.

Focus in the midgame on applying the crow to targets and supporting your team in the backline with damage and executes with the snipe
Tether enemies in the Alchemical Fire.

Warp Stone is great for escaping by warping on top of roofs
Debuff Remover for Knockdowns
Toxic Bullets vs tanky comps.

Build into applying debuffs to enemies
Toxic bullets can be bought earlier if the enemy team has a lot of healing.

Ethereal Shift is all around the best defensive item on Vindicta
Divine Barrier best all around.