Naro's Roaming airstrike

Items to help you lane
Buy situational if too hard
BUY IN ORDER

These items will help you gank enemies and farm quick
BUY IN ORDER

Extra survivability

These items will help you use your dome effectively
BUY IN ORDER

Sell your melee items
Swap Hi-velo for Crippling
Sell Berserker for S Overflow
DO NOT SELL HEALING BOOSTER
Sell healbane late-ish if you need space for Unstoppable
PUT RERVEB ON THE GRENADE FOR THE LOVE OF GOD
Put duration on dome, not beam, trust me.

Silence Glyph > Curse (usually not needed)

At the start, you want to bully people with the beam and take advantage of your melee items to deal bonus damage and CS freely
Berserker + the melee items + cqc self 'nade can cause some crazy hp swings in your favor, try baiting ppl into going around corners or into veils so you can get a nice charged melee out, works wonders.

Your ult's and grenade's animations take priority over your charged melee animation, so you can often get a free hit when doming or self 'nading
When you get to the point of buying crippling, you may be already able to spam your skills and have to sell your melee items, so you need to shift your playstyle and stop with meleeing
Enough EE stacks + Imp Burst will make your enemies implode, so go for 'nade > beam > 'nade and watch the fireworks.

Your Ult + Beam can apply a 120% RoF reduction, this works against Haze's ultimate as well (speaking of Haze, just melee her during her ult, if you shoot you have a 50% chance to miss)
If you're certain you can kill someone, but not sure if you can chase them, don't be afraid to solo dome them
Speaking of dome, IT'S NOT A GET OUT OF JAIL FREE CARD, don't dome a fed person that likes being in enclosed spaces, you'll lose
SILENCE GLYPH IS GOATED, USE IT AND ABUSE IT.

Your milage may vary